TY - JOUR
T1 - Ultrasound assisted site-selective alkynylation of 2,3,5,6-tetrachloropyridines under Pd/C[sbnd]Cu catalysis
AU - Bhavani, Sallagundla
AU - Rambabu, Dandela
AU - Rao, Mandava Venkata Basaveswara
AU - Pal, Manojit
N1 - Publisher Copyright:
© 2016 The Authors
PY - 2019/12/1
Y1 - 2019/12/1
N2 - A convenient synthetic method has been developed for accessing 2,6-dialkynyl-3,5-dichloropyridine derivatives in acceptable to good yields. The methodology involved ultrasound assisted site-selective alkynylation of 2,3,5,6-tetrachloropyridines under Pd/C[sbnd]Cu catalysis. A variety of terminal alkynes were employed in this C[sbnd]C coupling reaction to afford the corresponding 2,6-dialkynyl-3,5-dichloropyridine derivatives.
AB - A convenient synthetic method has been developed for accessing 2,6-dialkynyl-3,5-dichloropyridine derivatives in acceptable to good yields. The methodology involved ultrasound assisted site-selective alkynylation of 2,3,5,6-tetrachloropyridines under Pd/C[sbnd]Cu catalysis. A variety of terminal alkynes were employed in this C[sbnd]C coupling reaction to afford the corresponding 2,6-dialkynyl-3,5-dichloropyridine derivatives.
KW - Alkynes
KW - Pd/C
KW - Pyridine
KW - Ultrasound
UR - http://www.scopus.com/inward/record.url?scp=84976466580&partnerID=8YFLogxK
U2 - 10.1016/j.arabjc.2016.05.003
DO - 10.1016/j.arabjc.2016.05.003
M3 - Article
AN - SCOPUS:84976466580
SN - 1878-5352
VL - 12
SP - 4189
EP - 4196
JO - Arabian Journal of Chemistry
JF - Arabian Journal of Chemistry
IS - 8
ER -