Uncharged stereoregular nucleic acid analogs: 2. Morpholino nucleoside oligomers with carbamate internucleoside linkages

E. Subbotina; S. R.K. Koganti; D. M. Hodgson-Zingman; L. V. Zingman

doi:10.1002/cpt.276

Uncharged stereoregular nucleic acid analogs: 2. Morpholino nucleoside oligomers with carbamate internucleoside linkages

E. Subbotina, S. R.K. Koganti, D. M. Hodgson-Zingman, L. V. Zingman

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

The development of genetic and molecular biology tools permitting the connection of specific genes to their functions has accelerated our understanding of molecular pathways underlying health and disease. The resulting gains in knowledge have propelled gene targeting to the forefront of promising therapeutic strategies. Here we discuss the uniquely powerful and adaptable approach of morpholino-driven modification of normal and mutant gene expression as a pathway to health.

Original language	English
Pages (from-to)	21-25
Number of pages	5
Journal	Clinical Pharmacology and Therapeutics
Volume	99
Issue number	1
DOIs	https://doi.org/10.1002/cpt.276
State	Published - 1 Jan 2016
Externally published	Yes

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/cpt.276

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abstract = "The development of genetic and molecular biology tools permitting the connection of specific genes to their functions has accelerated our understanding of molecular pathways underlying health and disease. The resulting gains in knowledge have propelled gene targeting to the forefront of promising therapeutic strategies. Here we discuss the uniquely powerful and adaptable approach of morpholino-driven modification of normal and mutant gene expression as a pathway to health.",

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AU - Hodgson-Zingman, D. M.

AU - Zingman, L. V.

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Uncharged stereoregular nucleic acid analogs: 2. Morpholino nucleoside oligomers with carbamate internucleoside linkages

Abstract

ASJC Scopus subject areas

UN SDGs

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