Understanding the functionality of a biological system as a whole: Comparative data analysis

Isabel Orf

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

As part of a systems biology approach, metabolomics often aim at broadening our understanding of the functionality of biological systems as a whole. Observations from stand-alone experiments may reveal interesting changes in metabolites of a specific pathway or metabolite class. However, bringing these observations into context with more general biological processes requires the integration and comparison of different datasets. This chapter aims at introducing and explaining methods of comparative data analysis for plant metabolomics using the statistical software framework R.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages311-319
Number of pages9
DOIs
StatePublished - 1 Jan 2018

Publication series

NameMethods in Molecular Biology
Volume1778
ISSN (Print)1064-3745

Keywords

  • Clustering
  • Comparative analysis
  • Correlation
  • Data integration
  • R programing language
  • R software packages
  • Summary statistics
  • Systems biology

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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