Unexpected and Rare Sites of Metastasis in Oncologic Patients

Walid Shalata, Ashraf Abu Jama, Amjad Abu Salman, Mitchell Golosky, Adam Solomon, Omar Abu Saleh, Regina Michlin, Sondos Shalata, Abed Agbarya, Alexander Yakobson

Research output: Contribution to journalArticlepeer-review


Case studies of rare oncologic metastases are an important source of clinical data for health care professionals and researchers. While infrequent, the knowledge base and clinical recommendations derived from such cases aid in advancements in the field. As such, we aim to add five cases to the growing body of literature. The first two male patients, aged 69 and 73, were diagnosed with colon adenocarcinoma, suspected to be a second primary prostate carcinoma, following positron emission tomography-computer tomography (PET-CT). This suspicion was ruled out by prostatectomy and histopathological investigations, which instead found adenocarcinoma of colonic origin. The next two male patients, ages 63 and 68, were diagnosed, respectively, with metastatic pancreatic adenocarcinoma with cardiac metastases and metastatic melanoma with distant metastases to the pancreas. The final patient was a 73-year-old male diagnosed with metastatic breast cancer after a radiological investigation of suspected renal cell carcinoma.

Original languageEnglish
Article number6447
JournalJournal of Clinical Medicine
Issue number20
StatePublished - 1 Oct 2023
Externally publishedYes


  • colon cancer
  • male breast cancer
  • melanoma
  • oncologic patients
  • pancreatic cancer
  • rare metastasis
  • second primary

ASJC Scopus subject areas

  • General Medicine


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