Unilateral ophthalmoplegia secondary to anterior clinoid process mucocele

Boaz Forer, Ng Yuk Hui, Dharmbir Singh Sethi

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


A 50-year-old Chinese man presented with rapidly progressive unilateral ophthalmoplegia and then an ipsilateral afferent pupil defect. CT and MRI revealed a mass centered in the anterior clinoid process causing bone destruction and showing high T1 and T2 signal intensity indicative of mucosal protein secretion. These imaging features suggested a mucocele, which may have resulted from sequestration of a clinoidal extension of the sphenoid sinus. The sphenoid sinus was opened via an image-guided endoscopic approach, and the lesion incised. There were no complications. The ophthalmoplegia and afferent pupil defect had completely resolved within 1 week of surgery. This is the eighth reported case of anterior clinoidal mucocele, a rare cause of ophthalmoplegia or optic neuropathy. Advances in endoscopic instrumentation, navigation systems, and intraoperative imaging have reduced the operative risk and made the endoscopic approach a feasible and safer alternative to open surgery for this condition.

Original languageEnglish
Pages (from-to)321-324
Number of pages4
JournalJournal of Neuro-Ophthalmology
Issue number4
StatePublished - 1 Dec 2010
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology


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