Universal Model for Ion Transport: Bridging The Goldman-Hodgkin-Katz Paradigm with Reverse Electrodialysis

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1 Scopus citations

Abstract

The Goldman-Hodgkin-Katz (GHK) theory has been the paradigm for ion transport in physiological systems for the past century. However, GHK incorrectly assumes a uniform electrical field, leading to several inconsistencies. We propose a new theory developed using methods from the reverse-electrodialysis (RED) community. Our theory, substantiated by simulations, provides expressions for all the main characteristics of ion transport and connects GHK to RED, providing a remarkably robust framework for (re-)interpreting ion transport experiments in any (living or inanimate) charge-selective system.

Original languageEnglish
Pages (from-to)228401
Number of pages1
JournalPhysical Review Letters
Volume134
Issue number22
DOIs
StatePublished - 6 Jun 2025

ASJC Scopus subject areas

  • General Physics and Astronomy

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