Upconversion Nanodevice-Assisted Healthy Molecular Photocorrection

Kamaljit Kaur; Pulkit Bindra; Sanjit Mondal; Wei Peng Li; Sandeep Sharma; Bandana Kumari Sahu; Boddu S. Naidu; Chen Sheng Yeh; Ujjal K. Gautam; Vijayakumar Shanmugam

doi:10.1021/acsbiomaterials.0c01244

Upconversion Nanodevice-Assisted Healthy Molecular Photocorrection

Kamaljit Kaur, Pulkit Bindra, Sanjit Mondal, Wei Peng Li, Sandeep Sharma, Bandana Kumari Sahu, Boddu S. Naidu, Chen Sheng Yeh, Ujjal K. Gautam, Vijayakumar Shanmugam

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Mushrooms are rich in ergosterol, a precursor of ergocalciferol, which is a type of vitamin D2. The conversion of ergosterol to ergocalciferol takes place in the presence of UV radiation by the cleavage of the "B-ring"in the ergosterol. As the UV radiation cannot penetrate deep into the tissue, only minimal increase occurs in sunlight. In this study, upconversion nanoparticles with the property to convert deep-penetrating near-infrared radiation to UV radiation have been cast into a disk to use sunlight and emit UV radiation for vitamin D conversion. An engineered upconversion nanoparticle (UCNP) disk with maximum particles and limited clusters demonstrates ∼2.5 times enhanced vitamin D2 conversion.

Original language	English
Pages (from-to)	291-298
Number of pages	8
Journal	ACS Biomaterials Science and Engineering
Volume	7
Issue number	1
DOIs	https://doi.org/10.1021/acsbiomaterials.0c01244
State	Published - 11 Jan 2021
Externally published	Yes

Keywords

UCNP device
mushroom
nanoagri
nutrition
vitamin D

ASJC Scopus subject areas

Biomaterials
Biomedical Engineering

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10.1021/acsbiomaterials.0c01244

Cite this

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title = "Upconversion Nanodevice-Assisted Healthy Molecular Photocorrection",

abstract = "Mushrooms are rich in ergosterol, a precursor of ergocalciferol, which is a type of vitamin D2. The conversion of ergosterol to ergocalciferol takes place in the presence of UV radiation by the cleavage of the {"}B-ring{"}in the ergosterol. As the UV radiation cannot penetrate deep into the tissue, only minimal increase occurs in sunlight. In this study, upconversion nanoparticles with the property to convert deep-penetrating near-infrared radiation to UV radiation have been cast into a disk to use sunlight and emit UV radiation for vitamin D conversion. An engineered upconversion nanoparticle (UCNP) disk with maximum particles and limited clusters demonstrates ∼2.5 times enhanced vitamin D2 conversion.",

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AU - Kaur, Kamaljit

AU - Bindra, Pulkit

AU - Mondal, Sanjit

AU - Li, Wei Peng

AU - Sharma, Sandeep

AU - Sahu, Bandana Kumari

AU - Naidu, Boddu S.

AU - Yeh, Chen Sheng

AU - Gautam, Ujjal K.

AU - Shanmugam, Vijayakumar

N1 - Publisher Copyright: ©

PY - 2021/1/11

Y1 - 2021/1/11

N2 - Mushrooms are rich in ergosterol, a precursor of ergocalciferol, which is a type of vitamin D2. The conversion of ergosterol to ergocalciferol takes place in the presence of UV radiation by the cleavage of the "B-ring"in the ergosterol. As the UV radiation cannot penetrate deep into the tissue, only minimal increase occurs in sunlight. In this study, upconversion nanoparticles with the property to convert deep-penetrating near-infrared radiation to UV radiation have been cast into a disk to use sunlight and emit UV radiation for vitamin D conversion. An engineered upconversion nanoparticle (UCNP) disk with maximum particles and limited clusters demonstrates ∼2.5 times enhanced vitamin D2 conversion.

AB - Mushrooms are rich in ergosterol, a precursor of ergocalciferol, which is a type of vitamin D2. The conversion of ergosterol to ergocalciferol takes place in the presence of UV radiation by the cleavage of the "B-ring"in the ergosterol. As the UV radiation cannot penetrate deep into the tissue, only minimal increase occurs in sunlight. In this study, upconversion nanoparticles with the property to convert deep-penetrating near-infrared radiation to UV radiation have been cast into a disk to use sunlight and emit UV radiation for vitamin D conversion. An engineered upconversion nanoparticle (UCNP) disk with maximum particles and limited clusters demonstrates ∼2.5 times enhanced vitamin D2 conversion.

KW - UCNP device

KW - mushroom

KW - nanoagri

KW - nutrition

KW - vitamin D

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Upconversion Nanodevice-Assisted Healthy Molecular Photocorrection

Abstract

Keywords

ASJC Scopus subject areas

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