Use of electron-spin-resonance spectroscopy for studying the conformational states of peptides gramicidin S

V. T. Ivanov; A. I. Miroshnikov; L. G. Snezhkova; Yu A. Ovchinnikov; A. V. Kulikov; G. I. Likhtenshtein

doi:10.1007/BF00580899

Use of electron-spin-resonance spectroscopy for studying the conformational states of peptides gramicidin S

V. T. Ivanov, A. I. Miroshnikov, L. G. Snezhkova, Yu A. Ovchinnikov, A. V. Kulikov, G. I. Likhtenshtein

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

1. A new method has been proposed for studying the conformational states of peptides in solutions which is based on a consideration of the ESR spectra of their spin-labeled derivatives. 2. The synthesis of derivatives of gramicidin S containing one and two iminoxyl radicals in the²Orn and⁷Orn side chains has been effected. 3. On the basis of an analysis of the ESR spectra of the compounds obtained at -196°C and 30-62°C, conformations of the side chains of modified ornithine residues in chloroform and ethanol have been proposed.

Original language	English
Pages (from-to)	82-87
Number of pages	6
Journal	Chemistry of Natural Compounds
Volume	9
Issue number	1
DOIs	https://doi.org/10.1007/BF00580899
State	Published - 1 Jan 1973

ASJC Scopus subject areas

General Chemistry
General Biochemistry, Genetics and Molecular Biology
Plant Science

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10.1007/BF00580899

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title = "Use of electron-spin-resonance spectroscopy for studying the conformational states of peptides gramicidin S",

abstract = "1. A new method has been proposed for studying the conformational states of peptides in solutions which is based on a consideration of the ESR spectra of their spin-labeled derivatives. 2. The synthesis of derivatives of gramicidin S containing one and two iminoxyl radicals in the2Orn and7Orn side chains has been effected. 3. On the basis of an analysis of the ESR spectra of the compounds obtained at -196°C and 30-62°C, conformations of the side chains of modified ornithine residues in chloroform and ethanol have been proposed.",

author = "Ivanov, {V. T.} and Miroshnikov, {A. I.} and Snezhkova, {L. G.} and Ovchinnikov, {Yu A.} and Kulikov, {A. V.} and Likhtenshtein, {G. I.}",

year = "1973",

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doi = "10.1007/BF00580899",

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T1 - Use of electron-spin-resonance spectroscopy for studying the conformational states of peptides gramicidin S

AU - Ivanov, V. T.

AU - Miroshnikov, A. I.

AU - Snezhkova, L. G.

AU - Ovchinnikov, Yu A.

AU - Kulikov, A. V.

AU - Likhtenshtein, G. I.

PY - 1973/1/1

Y1 - 1973/1/1

N2 - 1. A new method has been proposed for studying the conformational states of peptides in solutions which is based on a consideration of the ESR spectra of their spin-labeled derivatives. 2. The synthesis of derivatives of gramicidin S containing one and two iminoxyl radicals in the2Orn and7Orn side chains has been effected. 3. On the basis of an analysis of the ESR spectra of the compounds obtained at -196°C and 30-62°C, conformations of the side chains of modified ornithine residues in chloroform and ethanol have been proposed.

AB - 1. A new method has been proposed for studying the conformational states of peptides in solutions which is based on a consideration of the ESR spectra of their spin-labeled derivatives. 2. The synthesis of derivatives of gramicidin S containing one and two iminoxyl radicals in the2Orn and7Orn side chains has been effected. 3. On the basis of an analysis of the ESR spectra of the compounds obtained at -196°C and 30-62°C, conformations of the side chains of modified ornithine residues in chloroform and ethanol have been proposed.

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U2 - 10.1007/BF00580899

DO - 10.1007/BF00580899

M3 - Article

AN - SCOPUS:34250397187

SN - 0009-3130

VL - 9

SP - 82

EP - 87

JO - Chemistry of Natural Compounds

JF - Chemistry of Natural Compounds

IS - 1

ER -

Use of electron-spin-resonance spectroscopy for studying the conformational states of peptides gramicidin S

Abstract

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