Use of gentamicin collagen sponges for the treatment of periprosthetic breast implant infection

Oren Lapid

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

The infection of a breast implant or tissue expander is a major complication with significant psychological and medical ramifications. The incidence has been reported to range from 1.1% in cosmetic augmentations to as high to 24% in a series of reconstructive cases. Gentamicin Surgical Implant is a surgical implant comprised of a lyophilised collagen matrix impregnated with a broad-spectrum antibiotic. When placed in the operative field, it achieves very high local concentrations of drug several fold above the minimal inhibitory concentrations; and the collagen carrier is absorbed. Its beneficial use has been reported in other fields of surgery. Gentamicin sponges were used in four cases of periprosthetic infections. The implants were removed, the pockets cleaned with pulse lavage and the implants were replaced, together with a gentamicin collagen implant. This was followed by a 6-week systemic antibiotic regimen. The patients had uneventful recovery and have not developed capsular contracture. Gentamicin collagen sponges may be used as an adjunct in the salvage of infected breast implants. Periprosthetic infections, as well as the use of gentamicin, are reviewed.

Original languageEnglish
Pages (from-to)e313-e316
JournalJournal of Plastic, Reconstructive and Aesthetic Surgery
Volume64
Issue number12
DOIs
StatePublished - 1 Dec 2011
Externally publishedYes

Keywords

  • Breast
  • Breast implant
  • Breast reconstruction
  • Complication
  • Gentamicin
  • Periprosthetic infection

Fingerprint

Dive into the research topics of 'Use of gentamicin collagen sponges for the treatment of periprosthetic breast implant infection'. Together they form a unique fingerprint.

Cite this