Use of the forced oscillation technique to detect bronchodilation in children: Experience from the Schneider children's medical center of Israel

Ephraim Bar-Yishay, Elena Matuyashchuk, Huda Mussaffi, Mier Mei-Zahav, Dario Prais, Shai Hananya, Guy Steuer, Hannah Blau

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Background: The forced oscillation technique is a non-invasive and effort-independent technique that is well suited for lung function measurement in young children. FOT employs small-amplitude pressure oscillations super-imposed on normal breathing. Therefore, it has the advantage over conventional lung function techniques in that it does not require patient cooperation for conducting respiratory maneuvers. Objectives: To test the feasibility of the FOT test in preschool children and to compare the results to the commonly used spirometry before and after the administration of bronchodilator therapy. Methods: Forty-six children (median age 4.9 years, range 1.8-18.3) attending the pulmonary clinic at Schneider Children's Medical Center tried to perform FOT and routine spirometry. Results were retrospectively analyzed. Results: Of the 46 children 40 succeeded in performing FOT and only 29 succeeded in performing simple spirometry. All but one of the 32 children aged 4 years and above (97%) could perform both tests. Nine of 14 children (64%) aged 4 and less could perform the FOT but only 3 (21%) could perform spirometry. Baseline values of respiratory resistance measured at 6 Hz (R6) negatively correlated with body length (r2 = 0.68, P < 0.005). Twenty-four children performed both tests before and after bronchodilator therapy. A significant concordance was found between the measured responses to bronchodilators by FOT and spirometry (P < 0.01). Only one child had a negative response by FOT but a positive response by spirometry. Conclusions: The FOT is a simple, non-invasive technique that does not require subject cooperation and thus can be utilized for measuring lung function in children as young as 2 years old. Furthermore, the FOT was shown to reliably measure response to bronchodilator therapy.

Original languageEnglish
Pages (from-to)198-200
Number of pages3
JournalIsrael Medical Association Journal
Issue number4
StatePublished - 25 Jun 2009
Externally publishedYes


  • Bronchodilator therapy
  • Forced expired volume in 1 second
  • Maximal expiratory flow-volume maneuver
  • Preschool children

ASJC Scopus subject areas

  • General Medicine


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