Uterine leiomyoma among women who conceived following fertility treatment

Tamar Biderman-Madar, Eyal Sheiner, Amalia Levy, Gad Potashnik, Moshe Mazor

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Objective: The objective was to determine if uterine leiomyoma increases the risk of cesarean section (CS) among women who conceived following fertility treatment. Study design: The study population consisted of all women who conceived after fertility treatment with singleton gestation and who delivered between the years 1988 and 1999 in the Soroka University Medical Center. A comparison was performed between patients with and without uterine leiomyomas. The Mantel-Haenszel procedure was used to obtain the weighted odds ratio (OR) for CS, while controlling for confounding variables. Results: During the study period 1,995 women conceived following fertility treatment. Of these, 63 patients had uterine leiomyomas (3.2%). Women treated for fertility with uterine leiomyomas had statistically significant higher rates of CS than those without uterine leiomyomas (61.9% vs. 28.1%, OR=4.2, 95% CI 2.4-7.2; P<0.001). Stratified analysis (the Mantel-Haenszel technique) was used to control for possible confounders, such as gestational diabetes, hypertensive disorders, maternal age, failure of labor to progress, placental abruption, malpresentation, hydramnios, oligohydramnios, and a previous CS. None of those variables changed the significant association or explained the higher incidence of CS in the uterine leiomyoma group. Conclusions: Uterine leiomyoma is an independent risk factor for CS among women who conceived following fertility treatment.

Original languageEnglish
Pages (from-to)218-222
Number of pages5
JournalArchives of Gynecology and Obstetrics
Issue number3
StatePublished - 1 Sep 2005
Externally publishedYes


  • Cesarean section
  • Fertility treatment
  • Uterine leiomyoma

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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