Vaginal delivery in SARS-CoV-2-infected pregnant women in Israel: a multicenter prospective analysis

Amihai Rottenstreich, Abraham Tsur, Nava Braverman, Doron Kabiri, Shay Porat, Shmuel Benenson, Yonatan Oster, Hadas Allouche Kam, Asnat Walfisch, Yossi Bart, Raanan Meyer, Shirlee Jaffe Lifshitz, Uri Amikam, Tal Biron-Shental, Gal Cohen, Yael Sciaky-Tamir, Inbar Ben Shachar, Yoav Yinon, Benjamin Reubinoff

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Key Message: Among SARS-CoV-2-infected mothers, vaginal delivery rates were high and associated with favorable outcomes with no cases of neonatal COVID-19. Purpose: To investigate the mode of delivery and its impact on immediate neonatal outcome in SARS-CoV-2-infected women. Methods: A prospective study following pregnant women diagnosed with COVID-19 who delivered between March 15th and July 4th in seven university affiliated hospitals in Israel. Results: A total of 52 women with a confirmed diagnosis of COVID-19 delivered in the participating centers during the study period. The median gestational age at the time of delivery was 38 weeks, with 16 (30.8%) cases complicated by spontaneous preterm birth. Forty-three women (82.7%) underwent a trial of labor. The remaining 9 women underwent pre-labor cesarean delivery mostly due to obstetric indications, whereas one woman with a critical COVID-19 course underwent urgent cesarean delivery due to maternal deterioration. Among those who underwent a trial of labor (n = 43), 39 (90.7%) delivered vaginally, whereas 4 (9.3%) cases resulted in cesarean delivery. Neonatal RT-PCR nasopharyngeal swabs tested negative in all cases, and none of the infants developed pneumonia. No maternal and neonatal deaths were encountered. Conclusions: In this prospective study among SARS-CoV-2-infected mothers, vaginal delivery rates were high and associated with favorable outcomes with no cases of neonatal COVID-19. Our findings underscore that delivery management among SARS-CoV-2-infected mothers should be based on obstetric indications and may potentially reduce the high rates of cesarean delivery previously reported in this setting.

Original languageEnglish
Pages (from-to)1401-1405
Number of pages5
JournalArchives of Gynecology and Obstetrics
Volume303
Issue number6
DOIs
StatePublished - 1 Jun 2021
Externally publishedYes

Keywords

  • COVID-19
  • Delivery
  • Outcomes
  • Pregnancy
  • Vaginal

Fingerprint

Dive into the research topics of 'Vaginal delivery in SARS-CoV-2-infected pregnant women in Israel: a multicenter prospective analysis'. Together they form a unique fingerprint.

Cite this