Vascular lesions in genital lichen sclerosus in pediatric patients

Rivka Friedland, Dan Ben-Amitai, Elena Didkovsky, Meora Feinmesser, Alex Zvulunov

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations

    Abstract

    Background/Objectives: Lichen sclerosus is a rare, pruritic, mucocutaneous disease affecting mostly the anogenital area. Reports have occasionally associated lichen sclerosus with overlapping vascular lesions. This study explores this association in children. Methods: A retrospective study was conducted in the dermatology unit of a pediatric tertiary care medical center. Electronic medical records were searched for patients diagnosed with lichen sclerosus from 2006 to 2019. Review of the cases was performed to identify overlapping vascular lesions and review the clinical course of overlap cases. Results: Of 74 children diagnosed with lichen sclerosus during the study period, five (6.75%) had overlapping vascular lesions and genital lichen sclerosus. Four patients presented with reticular telangiectatic macules and patches (n = 4, 5.4%) that appeared at or shortly after disease onset; resolution occurred a few months after treatment initiation. The fifth patient presented with telangiectases that appeared more than 2 years after the onset of the first symptoms of lichen sclerosus (n = 1, 1.3%). Conclusion: Vascular lesions in children with genital lichen sclerosus are common and have variable clinical manifestations. Early appearance of reticular macules, patches, and papules is a variant of the disease and is followed by prompt resolution of these lesions. Pathogenesis is attributed to structural changes and repositioning of the papillary vascular plexus. These changes may be alarming to parents and therefore must be recognized by physicians to prevent unnecessary concern and investigations.

    Original languageEnglish
    Pages (from-to)849-852
    Number of pages4
    JournalPediatric Dermatology
    Volume37
    Issue number5
    DOIs
    StatePublished - 1 Sep 2020

    ASJC Scopus subject areas

    • Pediatrics, Perinatology, and Child Health
    • Dermatology

    Fingerprint

    Dive into the research topics of 'Vascular lesions in genital lichen sclerosus in pediatric patients'. Together they form a unique fingerprint.

    Cite this