Vector-borne infections: a hazard for adventure visitors to Israel

Dror Guberman, Daniel A. Vardy, Laurent Klapholz, Sidney N. Klaus

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Three vector-borne diseases, Mediterranean spotted fever, cave fever, and simple cutaneous leishmaniasis, are endemic to Israel. These diseases may pose a significant health hazard to visitors to this area. The objective of this article is to supply the essential information concerning these diseases to physicians who are unfamiliar with them, with the intention of preventing disease by better traveler education and enabling prompt recognition and treatment outside the endemic areas. Mediterranean spotted fever is a rickettsiosis transmitted by a dog tick and presenting as a high fever with headache and typical rash. Cave fever is a borrelial infection transmitted by a soft tick and presenting as a relapsing febrile disease. Both diseases can be prevented by avoiding endemic areas and ticks, and respond well to treatment with tetracycline. Cutaneous leishmaniasis is a protozoan infection of the skin transmitted by the sandfly and presenting as an indurated erythematous cutaneous nodule. It responds to topical paromomycin and to intralesional or systemic sodium stibogluconate, but the best policy is to take the proper precautions and avoid infection.

Original languageEnglish
Pages (from-to)254-262
Number of pages9
JournalJournal of Wilderness Medicine
Issue number3
StatePublished - 1 Jan 1994
Externally publishedYes


  • cave (relapsing) fever
  • leishmaniasis
  • spotted fever
  • travel medicine
  • vacation

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine


Dive into the research topics of 'Vector-borne infections: a hazard for adventure visitors to Israel'. Together they form a unique fingerprint.

Cite this