Ventricular dysfunction in children with obstructive sleep apnea: Radionuclide assessment

Asher Tal, Alberto Leiberman, Giora Margulis, Shaul Sofer

    Research output: Contribution to journalArticlepeer-review

    214 Scopus citations


    Ventricular function was evaluated using radionuclide ventriculography in 27 children with oropharyngeal obstruction and clinical features of obstructive sleep apnea. Their mean age was 3.5 years (9 months to 7.5 years). Conventional clinical assessment did not detect cardiac involvement in 25 of 27 children; however, reduced right ventricular ejection fraction (less than 35%) was found in 10 (37%) patients (mean: 19.5 ± 2.3% SE, range: 8–28%). In 18 patients wall motion abnormality was detected. In 11 children in whom radionuclide ventriculography was performed before and after adenotonsillectomy, right ventricular ejection fraction rose from 24.4 ± 3.4% to 46.7 ± 3.4% (P < 0.005), and in all cases wall motion showed a definite improvement. In five children, left ventricular ejection fraction rose > 10% after removal of oropharyngeal obstruction. It is concluded that right ventricular function may be compromised in children with obstructive sleep apnea secondary to adenotonsillar hypertrophy, even before clinical signs of cardiac involvement are present.

    Original languageEnglish
    Pages (from-to)139-143
    Number of pages5
    JournalPediatric Pulmonology
    Issue number3
    StatePublished - 1 Jan 1988


    • Key words: Oropharyngeal obstruction
    • adeno‐tonsillectomy
    • cor pulmonale
    • radionuclide ventriculography
    • upper airway obstruction

    ASJC Scopus subject areas

    • Pediatrics, Perinatology, and Child Health
    • Pulmonary and Respiratory Medicine


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