Visualization of membrane processes in living cells by surface-attached chromatic polymer patches

Zulfiya Orynbayeva, Sofiya Kolusheva, Etta Livneh, Alexandra Lichtenshtein, Ilana Nathan, Raz Jelinek

Research output: Contribution to journalArticlepeer-review

58 Scopus citations

Abstract

Patch work: Through attachment of chromatic polydiacetylene (PDA) nanopatches onto the plasma membrane, real-time visualization of surface processes in living cells is possible (see picture; scale bar: 10 μm). The membrane-incorporated polymer patches did not adversely affect cell vitality for several hours and responded to structural perturbations of the plasma membrane both through induction of fluorescence as well as by undergoing blue-red color changes.

Original languageEnglish
Pages (from-to)1092-1096
Number of pages5
JournalAngewandte Chemie - International Edition
Volume44
Issue number7
DOIs
StatePublished - 4 Feb 2005

Keywords

  • Cell imaging
  • Fluorescent probes
  • Membrane processes
  • Scanning probe microscopy
  • Vesicles

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry

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