VOLTAGE DEPENDENT ANION CHANNEL (VDAC1) COMPOSITIONS AND METHODS OF USE THEREOF FOR REGULATING APOPTOSIS

Varda Shoshan-Barmatz; Salah Abu-Hamad; Laetitia Arzoine; Hilal Zaid

VOLTAGE DEPENDENT ANION CHANNEL (VDAC1) COMPOSITIONS AND METHODS OF USE THEREOF FOR REGULATING APOPTOSIS

Varda Shoshan-Barmatz (Inventor), Salah Abu-Hamad (Inventor), Laetitia Arzoine (Inventor), Hilal Zaid (Inventor)

Department of Life Sciences

Research output: Patent

Abstract

The present invention relates generally to the mitochondrial protein, voltage-dependent anion channel (VDAC)5 polynucleotides encoding same and variants thereof, as well as peptide fragments, peptide derivatives and analogs. In particular, the present invention is directed to VDAC1 and specific amino acid and polynucleotide sequences thereof useful in inducing or regulating apoptosis and to pharmaceutical compositions comprising same useful in the treatment of diseases associated with aberrant apoptosis.

Original language	English
Patent number	EP1856145
IPC	C07K 14/ 705 A I
Priority date	9/03/06
State	Published - 21 Nov 2007

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title = "VOLTAGE DEPENDENT ANION CHANNEL (VDAC1) COMPOSITIONS AND METHODS OF USE THEREOF FOR REGULATING APOPTOSIS",

abstract = "The present invention relates generally to the mitochondrial protein, voltage-dependent anion channel (VDAC)5 polynucleotides encoding same and variants thereof, as well as peptide fragments, peptide derivatives and analogs. In particular, the present invention is directed to VDAC1 and specific amino acid and polynucleotide sequences thereof useful in inducing or regulating apoptosis and to pharmaceutical compositions comprising same useful in the treatment of diseases associated with aberrant apoptosis.",

author = "Varda Shoshan-Barmatz and Salah Abu-Hamad and Laetitia Arzoine and Hilal Zaid",

year = "2007",

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T1 - VOLTAGE DEPENDENT ANION CHANNEL (VDAC1) COMPOSITIONS AND METHODS OF USE THEREOF FOR REGULATING APOPTOSIS

AU - Shoshan-Barmatz, Varda

AU - Abu-Hamad, Salah

AU - Arzoine, Laetitia

AU - Zaid, Hilal

PY - 2007/11/21

Y1 - 2007/11/21

N2 - The present invention relates generally to the mitochondrial protein, voltage-dependent anion channel (VDAC)5 polynucleotides encoding same and variants thereof, as well as peptide fragments, peptide derivatives and analogs. In particular, the present invention is directed to VDAC1 and specific amino acid and polynucleotide sequences thereof useful in inducing or regulating apoptosis and to pharmaceutical compositions comprising same useful in the treatment of diseases associated with aberrant apoptosis.

AB - The present invention relates generally to the mitochondrial protein, voltage-dependent anion channel (VDAC)5 polynucleotides encoding same and variants thereof, as well as peptide fragments, peptide derivatives and analogs. In particular, the present invention is directed to VDAC1 and specific amino acid and polynucleotide sequences thereof useful in inducing or regulating apoptosis and to pharmaceutical compositions comprising same useful in the treatment of diseases associated with aberrant apoptosis.

M3 - Patent

M1 - EP1856145

ER -

VOLTAGE DEPENDENT ANION CHANNEL (VDAC1) COMPOSITIONS AND METHODS OF USE THEREOF FOR REGULATING APOPTOSIS

Abstract

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