Abstract
The present invention relates generally to the mitochondrial protein, voltage-dependent anion channel (VDAC)5 polynucleotides encoding same and variants thereof, as well as peptide fragments, peptide derivatives and analogs. In particular, the present invention is directed to VDAC1 and specific amino acid and polynucleotide sequences thereof useful in inducing or regulating apoptosis and to pharmaceutical compositions comprising same useful in the treatment of diseases associated with aberrant apoptosis.
| Original language | English |
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| Patent number | EP1856145 |
| IPC | C07K 14/ 705 A I |
| Priority date | 9/03/06 |
| State | Published - 21 Nov 2007 |