TY - JOUR
T1 - Vulvar Paget's Disease with an Underlying Sweat Gland Adenocarcinoma
AU - PIURA, BENJAMIN
AU - ZIRKIN, HOWARD J.
PY - 1988/1/1
Y1 - 1988/1/1
N2 - Abstract. Vulvar Paget's disease, in contrast to its mammary counterpart, has been found to be associated with an underlying apocrine sweat gland carcinoma in about only 1/4 of the cases. There are two principal theories regarding the pathogenesis of extramammary Paget's disease: (1) intraepidermal origin of the Paget cells occurring independently of, or concomitantly with, an underlying apocrine gland carcinoma, and (2) the migration or metastasis of Paget cells into the epidermis from the underlying apocrine glands and/or ducts. A case of vulvar Paget's disease that, in our opinion, supports the theory of apocrine gland origin of Paget cells is reported herein. 1988 American Society for Dermatologic Surgery, Inc.
AB - Abstract. Vulvar Paget's disease, in contrast to its mammary counterpart, has been found to be associated with an underlying apocrine sweat gland carcinoma in about only 1/4 of the cases. There are two principal theories regarding the pathogenesis of extramammary Paget's disease: (1) intraepidermal origin of the Paget cells occurring independently of, or concomitantly with, an underlying apocrine gland carcinoma, and (2) the migration or metastasis of Paget cells into the epidermis from the underlying apocrine glands and/or ducts. A case of vulvar Paget's disease that, in our opinion, supports the theory of apocrine gland origin of Paget cells is reported herein. 1988 American Society for Dermatologic Surgery, Inc.
UR - http://www.scopus.com/inward/record.url?scp=0023884411&partnerID=8YFLogxK
U2 - 10.1111/j.1524-4725.1988.tb01148.x
DO - 10.1111/j.1524-4725.1988.tb01148.x
M3 - Article
C2 - 2834426
AN - SCOPUS:0023884411
SN - 0148-0812
VL - 14
SP - 533
EP - 537
JO - Dermatologic Surgery
JF - Dermatologic Surgery
IS - 5
ER -
