Translated title of the contribution: Why do we need to objectify the 'depth of anaesthesia'?

G. M. Gurman

    Research output: Contribution to journalReview articlepeer-review

    3 Scopus citations


    Despite intensive efforts, we still do not have generally accepted definition of the 'depth of anaesthesia'. While Prys-Roberts considers the loss of consciousness during general anaesthesia to be an all or nothing event, Jones is of the opinion that general anaesthesia can be subdivided into several stages depending upon the presence of intraoperative awareness and/or amnesia. Definition of the 'depth of anaesthesia' by using auxiliary constructs, such as MAC and ED50 is controversial because muscle activity does not represent a measure of cerebral activity during anaesthesia. The applicability of the EEG and the parameters derived from it as the sole measure of 'depth of anaesthesia' is limited by the fact that modern anaesthesia is usually performed by administering a combination of several drugs with differing action profiles whose effects on the cerebral activity mutually influence each other. More recent investigations, however, seem to indicate that a combination of clinical signs and several parameters of cerebral activity may solve the problem of measuring the 'depth of anaesthesia' in the future.

    Translated title of the contributionWhy do we need to objectify the 'depth of anaesthesia'?
    Original languageGerman
    Pages (from-to)50-56
    Number of pages7
    JournalAnasthesiologie und Intensivmedizin
    Issue number3
    StatePublished - 1 Jan 1995


    • anesthesia, general
    • awareness
    • electroencephalography
    • intraoperative care
    • monitoring, physiologic

    ASJC Scopus subject areas

    • Critical Care and Intensive Care Medicine
    • Anesthesiology and Pain Medicine


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