Abstract
Among the plethora of bioreactors available for aerobic culture, bubble columns, which are composed of a cylindrical vessel fitted with a gas sparger, are gaining in use. The simple construction of bubble-column reactors makes them easy to maintain. In addition, it is possible to control the degree of shear, uniformly within the reactor, which is critical to the growth of plant and animal cells in particular. This article reviews in detail the hydrodynamic, heat and mass-transfer characteristics of bubble-column bioreactors - parameters that are important for industrial scale-up.
| Original language | English |
|---|---|
| Pages (from-to) | 501-511 |
| Number of pages | 11 |
| Journal | Trends in Biotechnology |
| Volume | 12 |
| Issue number | 12 |
| DOIs | |
| State | Published - 1 Jan 1994 |
ASJC Scopus subject areas
- Biotechnology
- Bioengineering