WONOEP appraisal: Imaging biomarkers in epilepsy

Erwin A. van Vliet, Stefanie Dedeurwaerdere, Andrew J. Cole, Alon Friedman, Matthias J. Koepp, Heidrun Potschka, Riikka Immonen, Asla Pitkänen, Paolo Federico

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations

Abstract

Neuroimaging offers a wide range of opportunities to obtain information about neuronal activity, brain inflammation, blood–brain barrier alterations, and various molecular alterations during epileptogenesis or for the prediction of pharmacoresponsiveness as well as postoperative outcome. Imaging biomarkers were examined during the XIII Workshop on Neurobiology of Epilepsy (XIII WONOEP) organized in 2015 by the Neurobiology Commission of the International League Against Epilepsy (ILAE). Here we present an extended summary of the discussed issues and provide an overview of the current state of knowledge regarding the biomarker potential of different neuroimaging approaches for epilepsy.

Original languageEnglish
Pages (from-to)315-330
Number of pages16
JournalEpilepsia
Volume58
Issue number3
DOIs
StatePublished - 1 Mar 2017

Keywords

  • Biomarker
  • Blood–brain barrier
  • Epileptogenesis
  • Imaging
  • Inflammation
  • Traumatic brain injury

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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