Xenobiotics in Chemical Carcinogenesis: Translational Aspects in Toxicology

Akhileshwar Kumar Srivastava, Dhruv Kumar, Divya Singh, Rajesh Kumar Singh

Research output: Book/ReportBookpeer-review

Abstract

Xenobiotics in Chemical Carcinogenesis: Translational Aspects in Toxicology covers the translational toxicology of xenobiotics substances in carcinogenesis by explaining the toxicokinetic and toxicodynamic, toxicogenomic, biotransformation, and resistance mechanisms in the human body. The book begins with a historical review and link to future prospects for chemical carcinogenesis. It discusses major environmental xenobiotics and their risks in inducing cancer, along with content on toxic xenobiotics and their routes of exposure in humans, the role of xenobiotic metabolism in carcinogenesis, and the toxicokinetic and toxicodynamic of xenobiotics in cancer development. Lastly, the book explores current achievements such as using toxicogenomics for predicting the carcinogenicity of xenobiotic substances and the challenges posed by carcinogenic xenobiotic substances when examining preventive methods, diagnosis, and the development of anticancer drugs for specific toxicants.

Original languageEnglish
PublisherElsevier
Number of pages314
ISBN (Electronic)9780323905602
ISBN (Print)9780323906814
DOIs
StatePublished - 1 Jan 2022
Externally publishedYes

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (all)
  • Biochemistry, Genetics and Molecular Biology (all)

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