Yb(OTf)3 catalyzed new cascade reaction: A facile assembly of fused quinazolinones

K. Siva Kumar; P. Mahesh Kumar; M. Appi Reddy; Md Ferozuddin; M. Sreenivasulu; Ahamed A. Jafar; G. R. Krishna; C. Malla Reddy; D. Rambabu; K. Shiva Kumar; Sarbani Pal; Manojit Pal

doi:10.1039/c1cc13695j

Yb(OTf)₃ catalyzed new cascade reaction: A facile assembly of fused quinazolinones

K. Siva Kumar, P. Mahesh Kumar, M. Appi Reddy, Md Ferozuddin, M. Sreenivasulu, Ahamed A. Jafar, G. R. Krishna, C. Malla Reddy, D. Rambabu, K. Shiva Kumar, Sarbani Pal, Manojit Pal

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

A one-pot Yb(iii)-mediated cascade reaction has been developed leading to small molecules based on a novel structural motif, i.e. quinazolin-4-one moiety fused with an isoquinoline ring, for potential inhibition of TNF-α.

Original language	English
Pages (from-to)	10263-10265
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	37
DOIs	https://doi.org/10.1039/c1cc13695j
State	Published - 7 Oct 2011
Externally published	Yes

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Catalysis
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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title = "Yb(OTf)3 catalyzed new cascade reaction: A facile assembly of fused quinazolinones",

abstract = "A one-pot Yb(iii)-mediated cascade reaction has been developed leading to small molecules based on a novel structural motif, i.e. quinazolin-4-one moiety fused with an isoquinoline ring, for potential inhibition of TNF-α.",

author = "Kumar, \{K. Siva\} and Kumar, \{P. Mahesh\} and Reddy, \{M. Appi\} and Md Ferozuddin and M. Sreenivasulu and Jafar, \{Ahamed A.\} and Krishna, \{G. R.\} and Reddy, \{C. Malla\} and D. Rambabu and \{Shiva Kumar\}, K. and Sarbani Pal and Manojit Pal",

year = "2011",

month = oct,

day = "7",

doi = "10.1039/c1cc13695j",

language = "English",

volume = "47",

pages = "10263--10265",

journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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T1 - Yb(OTf)3 catalyzed new cascade reaction

T2 - A facile assembly of fused quinazolinones

AU - Kumar, K. Siva

AU - Kumar, P. Mahesh

AU - Reddy, M. Appi

AU - Ferozuddin, Md

AU - Sreenivasulu, M.

AU - Jafar, Ahamed A.

AU - Krishna, G. R.

AU - Reddy, C. Malla

AU - Rambabu, D.

AU - Shiva Kumar, K.

AU - Pal, Sarbani

AU - Pal, Manojit

PY - 2011/10/7

Y1 - 2011/10/7

N2 - A one-pot Yb(iii)-mediated cascade reaction has been developed leading to small molecules based on a novel structural motif, i.e. quinazolin-4-one moiety fused with an isoquinoline ring, for potential inhibition of TNF-α.

AB - A one-pot Yb(iii)-mediated cascade reaction has been developed leading to small molecules based on a novel structural motif, i.e. quinazolin-4-one moiety fused with an isoquinoline ring, for potential inhibition of TNF-α.

UR - https://www.scopus.com/pages/publications/80052533239

U2 - 10.1039/c1cc13695j

DO - 10.1039/c1cc13695j

M3 - Article

C2 - 21858289

AN - SCOPUS:80052533239

SN - 1359-7345

VL - 47

SP - 10263

EP - 10265

JO - Chemical Communications

JF - Chemical Communications

IS - 37

ER -

Yb(OTf)₃ catalyzed new cascade reaction: A facile assembly of fused quinazolinones

Abstract

ASJC Scopus subject areas

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